Formulation and evaluation of neem extract hand sanitizer

Abstract

Objective: The present research has been undertaken for the formulation and evaluation of neem Extract of hand sanitizer. It is used for topical use for the local anaesthetic activity. Methods: Carbopol 934 was used as a polymer in various batches. The ratio of Carbopol 934 was changed for various batches. Developed Formulations of Physicochemical parameters such as percentage yield, drug content, pH, Viscosity, Spreadability, Extrudability and In-vitro Diffusion study were carried out for developed batches of Neem extract. Results: Viscosity studies of various formulations Exhibited that Formulation F3 was better than that of F1 and F2. From among all the developed formulation, F3 Shows better rheological properties and excellent Extrudability. pH of the F3 Batch is Sufficient to treat the bacteria. Percentage yield and drug content of F3 batch is better than other batches. Results shows that the concentration of Carbopol 934 gives the good rheological properties and drug contents. In-vitro Diffusion studies were carried out, F3 batch shows better results than that of the other two batches i.e. 99.06%. Conclusion: It was concluded that F3 batch is the better than that of other batches. So F3 batch is better for the topical use.