Abstract
The team nanogels, defined as nanoparticles composed of a hydrogel with a linked hydrophilic polymer network, are formed by physically or chemically cross-linking nanosized polymer networks that swell in a good solvent. By designing specific chemical structures and employing different production methods, nanogels can exhibit various responsiveness characteristics, including temperature sensitivity, pH sensitivity, and redox sensitivity. This enables the stimuli-responsive release of drugs within the micro-environments of different diseases. Moreover, this article provides a summary of the current status, clinical trial progress, and future perspectives of nanogels.
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