Abstract
Diseases have co-existed with life, the study of diseases and their treatment is important part of our ancient plant worldwide. Herbal plants are wonderful origin of traditional & modern medicine, useful for primary health care system. Herbal medicine prepare various part of plant are used. Instead off an herbal drug is design as the alternative formulation for the external use in the form of ointment. For the medicinal use the herbal ointment apply externally on human body. The main aims of this research are preparation of herbal ointment from the Acacia nilotica (L.) Delile plants the antibacterial activity. Under this research work, it is design as herbal ointment with the help of ethanolic extract of Acacia nilotica (L.) Delile determines the anti-bacterial capacity on it. In vitro study the antibacterial activity of the ethanolic extracts of dried leaves of Acacia nilotica (L.) Delile are determine by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the ethanolic extract of Acacia nilotica (L.) Delile (10 % w/w) into aqueous cream we formulated herbal ointment. The emulsifying agent and simple ointment bases are added in above herbal ointment for increase the antibacterial effectiveness during in vitro evaluation. Acacia nilotica (Family Leguminosae) are broadly used in traditional system of medicine throughout different part of India, Africa & America. It is used in the treatment of diarrhea, dysentery, cough, tuberculosis and leprosy. The current study deals with the determination of formulation and evaluation of herbal ointment using Acacia nilotica (L.) leave extract.
Highlights
In current days herbal ointment is more popular formulation use for external application
The aim of the study was to show that Acacia nilotica (L.) Delile are antibacterial activity and has high potential as antibacterial agent when synthesized as ointment for topical use ethanolic extract of Acacia nilotica (L.) Delile
In various case history show that most of the infections are caused by the gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes
Summary
In current days herbal ointment is more popular formulation use for external application. Instead of the alternative formulation like herbal medicine may be prepared in the form of ointment. These ointment mention a viscous semisolid preparation applied externally on body surfaces area such as the skin, mucus membranes of the eye, vagina, anus, and nose etc. The medicated ointments contain a medicinal ingredient mixed, suspended or emulsified in the ointment base. Ointment bases are mainly free from water and generally contain one or more chemical in suspension or solution or dispersion form. Ointment bases may be different types like absorption bases, dehydrating hydrocarbon water soluble type [2]
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