Abstract
Many European smelt, Osmerus eperlanus, in tributary rivers to the North Sea are affected by granulomatosis in the buccal cavity. The granulomas are caused by spines and leg fragments of amphipods, an important food item of smelt. Granuloma prevalence increases with increasing fish size. The rate of increase slows down in very large fish, probably as an effect of changed feeding habits. Fungi and virus-like particles in the granulomas are assumed to be secondary invaders. Granulomas are occasionally found in Atlantic cod, Gadus morhua, and flounder, Platichthys flesus, also.
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