Abstract
The ability of synthetic pteroylglutamic (folic) acid to induce hematologic remissions in patients with macrocytic anemia associated with megaloblastic hyperplasia of the bone marrow has been well established. A recent review by Berry and Spies 1 covers the subject adequately. While the results of treatment with folic acid appeared to be similar to or identical with those of treatment with purified extracts of liver, it was recognized 2 that a considerable period of study would be necessary to ascertain whether folic acid would be as effective as extracts of liver in the maintenance of remission. In pernicious anemia it was also of importance to determine whether folic acid would cause arrest of neurologic lesions as effectively as do extracts of liver. Recent reports 3 have indicated that in some patients with pernicious anemia there develops decided progression of neurologic lesions while they are being maintained on folic acid. The following
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
