Abstract
Focal epithelial hyperplasia, or Heck's disease, is a rare benign lesion of the oral mucosa. It is usually associated with the proliferation of the squamous epithelium mainly attributed to human papillomavirus (HPV). We report the case of a 38-year-old dark-skinned man who attended the health service of the university complaining of an oral mucosa burning sensation. On clinical examination, the patient presented multiple pink papular lesions, firm by palpation, with agglomerated or isolated papules located on the alveolar ridge, inserted and free gingiva of the upper and lower arch, and buccal and labial mucous membranes consistent with HPV lesions. Focal epithelial hyperplasia was the clinical diagnosis. An incisional biopsy of the oral lesions was performed, and the histopathology report described the fragment of oral mucosa covered by stratified parakeratinized squamous epithelium with prominent acanthosis and confluent focal projections to the connective tissue, corroborating the previous clinical diagnostic suspicion.
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