Abstract
Focal application of a hypertonic solution of sodium chloride to the atria or ventricles of the exposed heart of the dog leads to the appearance of coupled extrasystoles or short bouts of ectopic paroxysmal tachycardia 5. When 0.05 c.c. of a 20 per cent solution of sodium chloride is injected into the taenia terminalis, in which the sinus node is situated, and one of the vagus nerves is stimulated in the neck with a faradic current, atrial flutter, atrial fibrillation, or a paroxysmal atrial tachycardia appears 11. These effects are fleeting, and are observed for 4 to 5 minutes immediately following the injection. This investigation was continued and the effect of injections of the hypertonic solution in two other areas was studied: these areas were the atrioventricular node and the appendix of the left atrium, which is supposedly devoid of specialized automatic fibers.
Published Version
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