Abstract

• An overview of the synthesis of three-dimensional fluorescent cage-like chemosensors. • Applications of cage chemosensors in the fields of detection of anions and hazardous, biological and polyaromatic molecules. • The challenges and opportunities for the synthesis and application of fluorescent chemosensors. This review provides a general overview of the development of fluorescent chemosensors based on closed three-dimensional architectures and highlights selected examples from research groups which have made a significant contribution to this field. The basic principles and challenges involved in the design of cage-like fluorescence chemosensors for a variety of guest molecules are covered. Particular attention is paid to the use of molecular and supramolecular fluorescent architectures for the detection of explosives/hazardous substances, aromatics and biologically active compounds.

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