Abstract

Stenting is a common method for treating atherosclerosis. A metal or polymer stent is deployed to open the stenosed artery or vein. After the stent is deployed, the blood flow dynamics influence the mechanics by compressing and expanding the structure. If the stent does not respond properly to the resulting stress, vascular wall injury or re-stenosis can occur. In this work, a Discrete Multiphysics modelling approach is used to study the mechanical deformation of the coronary stent and its relationship with the blood flow dynamics. The major parameters responsible for deforming the stent are sorted in terms of dimensionless numbers and a relationship between the elastic forces in the stent and pressure forces in the fluid is established. The blood flow and the stiffness of the stent material contribute significantly to the stent deformation and affect its rate of deformation. The stress distribution in the stent is not uniform with the higher stresses occurring at the nodes of the structure. From the relationship (correlation) between the elastic force and the pressure force, depending on the type of material used for the stent, the model can be used to predict whether the stent is at risk of fracture or not after deployment.

Highlights

  • Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations

  • The plaque is deposited on the arterial wall, and this leads to the narrowing of the artery and subsequently obstruction of the blood flow known as stenosis

  • The liquid domain represents the blood, and it is modelled with Smooth Particle Hydrodynamics (SPH) particles; the solid domain represents the stent and the arterial walls and it is modelled with Lattice Spring Model (LSM) particles

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Summary

Introduction

The plaque is deposited on the arterial wall, and this leads to the narrowing of the artery and subsequently obstruction of the blood flow known as stenosis. This obstruction hinders the smooth transportation of blood through these arteries and poses a serious health problem. When atherosclerosis affects an artery that transports oxygenated blood to the heart, it is called coronary artery disease. Coronary artery disease is the most common heart disease that becomes the leading cause of death globally. Worldwide, it is associated with 17.8 million death annually [1]. The healthcare service for coronary artery disease poses a serious economic burden even on the developed countries, costing about 200 dollars annually in the United States

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