Abstract
Plant extracts and natural compounds show scientifically proven activity against numerous viruses, including the SARS-CoV-2 virus, responsible for causing COVID-19. Among plant constituents, polyphenolic compounds (flavonoids, phenolic acids, proanthocyanidins, catechins) show the greatest potential. Characteristic for plant extracts containing a mixture of secondary metabolites is the multidirectional action and improvement of the functioning of numerous tissues and organs. As a result, in addition to their antimicrobial activity, they alleviate a number of side effects caused by infection. They show anti-inflammatory properties and stimulate the immune system. Few clinical trials of the use of herbs, bee products, natural compounds, and vitamin D as an adjunct to standard therapies have confirmed their beneficial effects, both in patients with moderate and severe disease. Herbal preparations should be recommended both for prophylaxis and as an adjunct to standard COVID-19 treatment.
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