Abstract
Congenital diseases that affect the anterior segment are typically due to cranial neural crest defects. This transient embryonic stem cell population ultimately gives rise to the bone, cartilage, and connective tissue of the jaw and mid face, and within the eye contributes to the corneal, iris, ciliary body, aqueous outflow pathways, and sclera. Thus, due to their common origin, congenital eye anomalies are often associated with facial defects.
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