Abstract
Aim: The current research aims to design effective strategies to enhance the body's immune system against pathogenic bacteria. Methods: Skin commensals were isolated, identified and cultured in fish collagen peptides (FCPs). Results: After culturing in FCP, the skincommensals were used in a dose-dependent manner for Staphylococcus aureus in a dual-culture test, which showed significant growth inhibition of the pathogenic bacteria, which concluded that FCP induced the immune defense system of skin microbiota against pathogenic strains. Conclusion: Results havevalidated that fish collagen peptide plays a vital role in the growth of selected human skin flora and induces moredefensive immunity against pathogenic S. aureus bacteria in dual-culture experimentation.
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