Abstract
The Sri Lankan Journal of Infectious Diseases (SLJID) is an open access, peer-reviewed, biannual journal published by the Sri Lankan Society for Microbiology (SSM). The Journal considers articles from all professional disciplines involved in the field of infectious diseases. The Journal has been in publication since 2011, is included in the DOAJ since 2018 and is a member of COPE since 2021. The SLJID practices a double-blind peer review policy. From 2022, the SLJID publishes accepted manuscripts online immediately after copy-editing, enabling rapid dissemination of scientific knowledge. The published articles are subsequently compiled into two issues in April and October. The SLJID does not charge any article processing or publication fee.
Highlights
Pneumocystis pneumonia (PCP) caused by the fungus Pneumocystis jirovecii is an opportunistic infection that causes major infectious complications in immunocompromised patients.[1]
Molecular diagnosis and species identification was carried out using polymerase chain reaction (PCR), DNA sequence alignment, and phylogenetic analysis
Patient 1 was a 53-year-old female post-kidney transplant patient who was admitted with pneumonia to the surgical intensive-care unit (SICU) of the National Hospital, Kandy, Sri Lanka
Summary
Pneumocystis pneumonia (PCP) caused by the fungus Pneumocystis jirovecii is an opportunistic infection that causes major infectious complications in immunocompromised patients.[1]. Pneumocystis pneumonia (PCP) caused by the fungus Pneumocystis jirovecii is an opportunistic infection that causes major infectious complications in immunocompromised patients.[1] Kidney transplant patients have shown mortality rates from 29% to 50% due to PCP.[2] The risk for PCP development appears to be higher during the early period after transplantation.[2] A previous study in Sri Lanka stated that there was a lack of available data on PCP as it is diagnosed using histological staining procedures.[3] These are the first two patients in whom precise molecular diagnosis with DNA sequencing and phylogenetic analysis of P. jirovecii was carried out in Sri Lanka. Molecular diagnosis and species identification was carried out using polymerase chain reaction (PCR), DNA sequence alignment, and phylogenetic analysis.
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