Abstract
The detection of HIV-1 levels in human hosts is cast as a first exit time problem for a multidimensional diffusion process. We consider a four-component model for early HIV-1 dynamics including uninfected CD4+ T-cells, latently infected cells, actively infected cells, and HIV-1 virions. An analytical framework is presented for the distribution of the time at which a given virion level is attained. A one-dimensional diffusion approximation for a branching process leads to an estimate for the distribution of the virion density and an expression for the mean detection time for any given detection threshold.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
