Abstract
Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic and clinical studies related to cancer cell, cell biology, oncology, radiation therapy and radiology, obstetrics and gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.
Highlights
Among the leading adverse forms of acquired malignant diseases is human lung cancer representing ~17% of new cancer diagnoses worldwide
squamous cell carcinoma (SCC) derived from different human tissues, as well as lung SCC and non-small cell lung cancer, display overall similar copy number variations (CNVs) patterns
Conclusion: according to the genetic profile found here, KLN 205 can be applied as a general model for human SCC; it is suited as a model for lung cancer in general
Summary
Among the leading adverse forms of acquired malignant diseases is human lung cancer representing ~17% of new cancer diagnoses worldwide. Murine cancer cell lines are well established models to perform such studies[3,4,5]. Most of these murine cancer cell lines have never been (cyto)genetically characterised in detail, irrespective of how often they have already been used in research[6,7]. This is because murine chromosomes are hard to distinguish in banding cytogenetics[7]
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