Abstract
Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic and clinical studies related to cancer cell, cell biology, oncology, radiation therapy and radiology, obstetrics and gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.
Highlights
The prognosis of patients with head and neck squamous cell cancer (HNSCC) decreases with the presence of extranodal extension (ENE) in lymph node metastases
Locoregional recurrences and distant metastases account for the majority of treatment failures in head and neck squamous cell cancer (HNSCC)[1]
ENE was introduced in the 8th Edition TNM Classification (TNM8) for Head and Neck Cancer as an important staging variable in all HPV-negative HNSCC
Summary
The prognosis of patients with head and neck squamous cell cancer (HNSCC) decreases with the presence of extranodal extension (ENE) in lymph node metastases. Fewer reports are available on the detection of ENE with magnetic resonance imaging (MRI). The imaging features used to radiologically determine ENE are similar for CT and MRI. The pooled sensitivity for the detection of ENE was found to be 0.73 (95%CI: 0.62-0.82).
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