Abstract
Oncocytic carcinoma of the pancreas is a very rare variant of pancreatic ductal adenocarcinoma. Fine-needle aspiration biopsy reports of this tumor are exceptionally rare. We report the case of a 65-year-old female patient who presented with a mass in the head of the pancreas. The mass was sampled by fine-needle aspiration biopsy on 2 separate occasions, and both samples were diagnosed as oncocytic carcinoma of the pancreas. The patient underwent a Whipple resection, and histopathologic examination of the resection specimen showed an invasive oncocytic carcinoma arising from intraductal oncocytic papillary neoplasm with high-grade dysplasia. Here we discuss the cytologic and histological features, differential diagnoses, utility of ancillary studies, and the recently updated knowledge about this rare entity.
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