Abstract
Wiernik et al (1990) have reported on the BIR multicentre trial of 3 versus 5 days per week treatment of tumours of the larynx and pyriform sinus. No statistically significant differences were found between the two arms with respect to survival and complication rates. The purpose of choosing irradiation over surgery in the tumours of the laryngopharynx is to preserve the larynx. Salvage surgery is highly successful, primarily for failures in patients with mobile cord tumours, but it also has been successful in other sites where, in addition to laryngectomy, radical neck dissection can be curative. Therefore, survival rates do not reflect the effectiveness of the radiation treatment, yet survival analysis makes up the bulk of their report. The brief analysis of the incidence of laryngectomies is lost in an extensive text on statistical methods and a large number of tables and graphs relating to survival rates.
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