Fibromiyalji Sendromunda Demir Eksikliği ve Demir Eksikliği Anemisi Görülme Sıklığı

Abstract

ObjectiveFibromyalgia syndrome (FMS), which is a chronic pain condition of unknown etiology, is mainly characterized by widespread pain, sleep disturbances, memory problems, and fatigue, which seriously impair quality of life. Decreased production of biogenic amine neurotransmitters as a result of decreased iron levels in the blood may play a role in the pathophysiology of FMS. This study aimed to investigate the prevalence of iron-deficiency and iron-deficiency anemia in patients with FMS and to draw attention to the prevalence of iron deficiency in patients with FMS. Material and MethodsThe patients who applied to the physical medicine and rehabilitation outpatient clinic of our hospital in the last five years, who were diagnosed as FMS and whose serum ferritin, total iron-binding capacity (TDBK), vitamin B12 concentrations and plasma hemoglobin concentrations were determined were analyzed retrospectively. Data were analyzed by using SPSS 23 package program. ResultsIn the independent group comparisons between female and male patients with FMS, both plasma hemoglobin and serum iron levels were significantly lower in female patients than in male patients (p =0.009 and p = 0.002, respectively). There were no statistically significant differences between serum vitamin B12 levels and serum ferritin levels between male and female patients with FMS (p= 0.344, p=0,093 respectively). Besides, iron deficiency and iron deficiency anemia were observed in 28% and 12% of all FMS patients, respectively. Conclusion Measuring serum ferritin levels in FMS patients and treating iron deficiency when necessary is recommended to increase the success of FMS treatment.