Abstract
Fibrolipoma is a benign neoplasm characterized by the presence of mature adipose cells separated by broad bands of dense fibrous connective tissue. This pathology is a microscopic variant of lipoma and can affect any part of the body. However, its occurrence in the oral cavity is uncommon. It is usually a smooth-surface lesion, asymptomatic, slow-growing, pedicled, asymptomatic, yellowish or pinkish color when deeper, soft on palpation, occurring mainly in the jugal mucosa. Thus, the aim of this paper is to describe the main clinical, histopathological and treatment characteristics of a clinical case of fibrolipoma. A 67-year-old female patient, leukoderma, had a normochromic, asymptomatic, firm palpation nodule, fibrous consistency, and smooth surface, with a time course of approximately two years, located in the left jugal mucosa. The diagnostic hypotheses were lipoma, fibroma, mucus extravasation phenomenon and giant cell fibroma. The patient underwent excisional biopsy and histopathological examination revealed the definitive diagnosis of fibrolipoma. The patient is in preservation, with no sign of relapse. It is concluded that, although fibrolipoma is a benign lesion, its growth can reach large dimensions, reinforcing the need for surgical excision. It should also emphasize the importance of histopathological examination to differentiate histopathological variations of lipoma.
Highlights
O fibrolipoma é uma neoplasia benigna, caracterizada pela presença de células adiposas maduras, separadas por largas bandas de tecido conjuntivo fibroso denso
Fibrolipoma is a benign neoplasm characterized by the presence of mature adipose cells separated by broad bands of dense fibrous connective tissue
This pathology is a microscopic variant of lipoma and can affect any part of the body
Summary
O fibrolipoma é uma neoplasia benigna, caracterizada pela presença de células adiposas maduras, separadas por largas bandas de tecido conjuntivo fibroso denso. O fibrolipoma é uma variante do lipoma, representando aproximadamente 40% dos tumores benignos de tecido adiposo, caracterizado pela presença de tecido conjuntivo denso entremeando as células adiposas neoplásicas[2,4,5]. Por ter características comuns com outras patologias, os fibrolipomas apresentam diversos diagnósticos diferenciais, dependendo de sua localização dentro da cavidade bucal, como: a rânula, o cisto dermoide, o cisto do ducto tireoglosso, o adenoma pleomórfico, o granuloma piogênico, o linfangioma, o schwannoma, neoplasia de glândulas salivares, lipossarcoma, lipoma e o fibroma[10,11,12,13].
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