Abstract
IntroductionMucoceles are common benign pseudocystic lesions of the oral cavity; their main etiological factors are trauma and ductal obstruction. Two histological patterns are found: mucus retention phenomenon (MRP) and mucus extravasation phenomenon (MEP). Mucus extravasation phenomenon is the more common histological subtype and it mainly affects the lower lip. The knowledge of its main clinical features and management is important to assist health professionals in clinical practice. ObjectiveThis study aimed to determine the relative frequency and distribution of oral mucoceles in an oral pathology reference center. MethodsCross-sectional historical study that analyzed all cases pathologically diagnosed as mucus extravasation phenomenon by the department of anatomic pathology of an oral pathology referral center from June of 1970 to May of 2014, considering the clinical characteristics of the lesion and those relating to the patient. SPSS v. 20.0 software for Windows was used for descriptive analysis. ResultsDuring 43 years, 719 cases of mucus extravasation phenomenon (54.7% men and 45.3% women) were registered, with the lower lip as the most commonly affected site (n=484; 67.3%). The average age of patients was 20.8 years (SD±14.4) with a peak occurrence in the second decade of life. Most professionals had oral mucocele/ranula (n=606; 84.3%) as the initial clinical impression. ConclusionMucus extravasation phenomenon is a lesion that primarily affects young patients, affecting mainly the lower lip, and is commonly found in oral diagnostic services.
Highlights
Mucoceles are common benign pseudocystic lesions of the oral cavity; their main etiological factors are trauma and ductal obstruction
Mucoceles are common benign pseudocystic lesions of the oral cavity that develop secondary to leakage or retention of mucous material from salivary glands, principally the minor salivary glands.[1]
The 719 cases of oral mucoceles represent 5.8% of all cases registered by the oral pathology laboratory during the stated period
Summary
Mucoceles are common benign pseudocystic lesions of the oral cavity; their main etiological factors are trauma and ductal obstruction. Mucus extravasation phenomenon is the more common histological subtype and it mainly affects the lower lip. Methods: Cross-sectional historical study that analyzed all cases pathologically diagnosed as mucus extravasation phenomenon by the department of anatomic pathology of an oral pathology referral center from June of 1970 to May of 2014, considering the clinical characteristics of the lesion and those relating to the patient. Etiologic factors involved in mucocele formation include trauma and ductal obstrction,[3,4] which may lead to formation of two histological presentations: the phenomenon of mucus retention or extravasation.[1,5] The mucus extravasation phenomena (MEP) are pseudocysts, as they are devoid of epithelial lining. Most of these grow from major salivary glands and ducts and have the following etiological factors: sialolithiasis, periductal scarring, or invasive tumors.[5,7] Histopathologically, MRP are characterized by epithelium lining coming from the partially obstructed salivary duct.[4]
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