Abstract

Febrile neutropenia is an oncologic emergency that is seen in patients receiving chemotherapy. It is more commonly noted in hematologic malignancies, although it can be observed in solid tumor cancers. Management involves prompt infectious workup, determination of high or low risk using the Multinational Association for Supportive Care in Cancer risk index score, and initiation of empiric antimicrobials in the inpatient or outpatient setting. Close monitoring for organ dysfunction and worsening clinical status is essential. Nurse practitioners must identify risk factors, signs, and symptoms of febrile neutropenia and understand the proper management strategies for both high- and low-risk patients.

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