Abstract
Amniotic fluid creatinine, bilirubin, and cells as well as serum creatinine have been measured in an attempt to corroborate reported investigations which correlate these values with fetal maturation. An amniotic fluid creatinine value of 2 mg. per 100 ml. or more usually indicates a gestational age of at least 37 weeks. Absence of a bilirubin peak at 450 mμ, the presence of 20 per cent of cells which stain orange with Nile blue sulfate dye, or the presence of a ratio between amnotic fluid creatinine and serum creatinine of 3 or more usually indicates a gestational age of 36 weeks or more. Because a high percentage of these tests are negative beyond 36 to 37 weeks, no single value or combination of values provides absolute evidence of fetal maturation.
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