Abstract
✓ The capillaries in two cerebellar hemangioblastomas were studied by thin-section and freeze-fracture techniques. Fenestrae were found in the attenuated portions of the endothelium, and plasmalemmal vesicles in the nonfenestrated portions. In freeze-fracture preparations the fenestrae of the endothelial plasma membrane were about 450 to 550 A in diameter. They appeared as holes and “necks” in clusters of about 40 to 60 per µm2. When the fracture plane passed in a stepwise fashion from the luminal plasma membrane into the contraluminal plasma membrane, the fenestrae at the fracture edge involved both plasma membranes.
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