Abstract

患者女,58岁。肛周肿胀疼痛10余年,术后1年复发。切除肿物病理示:肿瘤细胞呈不规则索状、带状或片状排列,间隔以纤维组织;肿瘤细胞体积大,细胞边界不清,胞质丰富,嗜伊红细颗粒状,并见嗜伊红小体;散在凋亡小体及凝固性坏死灶;核分裂象2/10 HPF。免疫组织化学染色:CD68、S-100蛋白阳性,Ki-67阳性指数5%。特殊染色:胞质过碘酸-雪夫(PAS)染色及淀粉酶消化-过碘酸雪夫(D-PAS)染色阳性。诊断为(会阴部)恶性颗粒细胞瘤。.

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