Abstract
Background and Aims : It is the cumulative exposure to low-density lipoprotein cholesterol (LDL-C) that defines the risk of cardiovascular disease (CVD). Patients with familial hypercholesterolemia (FH) have increased risk of premature CVD, and the highest excess risk is observed in young FH women. The aim of our study was to calculate lifelong LDL-C burden in FH individuals and investigate possible sex differences.
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