Abstract
Omega‐3 polyunsaturated fatty acid (n‐3 PUFA) sources providing high bioavailability and tissue accretion with the least peroxidation favor maximal health benefits. The study objective was to determine the tissue accretion and stability of n‐3 PUFAs from different sources. Young (28 d) female Sprague‐Dawley rats (n=10/group) were pair‐fed high fat (12% lipid/wt) diets containing either corn oil (CO) or n‐3 PUFA rich oils derived from flaxseed (FO), krill (KO), or menhaden (MO). Rats were individually housed in metabolic cages to determine apparent lipid digestibility: [(lipid intake – fecal lipid)/(lipid intake)] x 100. After 8 wks, liver and brain tissue were collected. Tissue fatty acid content (FA) was determined by gas chromatography and lipid oxidation by enzyme immunoassay for Thiobarbituric Acid Reactive Substances (TBARS). Lipid digestibility was lowest (p<0.05) in KO fed rats. In the brain, docosahexaenoic acid (DHA) was highest (p<0.02) in rats fed KO. In the liver, alpha‐linolenic acid was highest (p<0.001) in rats fed FO; eicosapentaenoic acid was higher (p<0.001) in rats fed KO, MO, and FO compared to CO. DHA was highest (p<0.001) in rats fed KO and MO. TBARs were similar among diet groups. Different sources of n‐3 PUFAs had different effects. Despite low digestibility, KO increased tissue DHA content without increasing tissue oxidation. Funding NRI #1004489 USDA NIFA grant.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
