Abstract
Differences in the nature of the transition/transversion bias of birds and mammals, as well as families with small and large body-sized species, are proven by the example of the CYTB gene. It was that for birds compared to mammals, as well as in families of small birds and mammals compared to larger ones, the frequency of transversions is significantly higher and the frequency of transitions is lower. This leads to a decrease in the transition/transversion bias and a decrease in the rate of its evolutionary compensation. The possible cause of this phenomenon is the greater intensity of individual metabolism and the resulting increase in mutation rates in birds and small species. Exceptions are extremely small species that are characterized by a state of hypothermia. The high level of metabolism and mutability explains the richness of bird species, as well as the highest activity of speciation in small organisms. In addition, the transition/trans- version bias should be considered as a reliable integral indicator of individual metabolic intensity at the family level.
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