Features of the blood lipid spectrum in men exposed to elevated noise levels

Abstract

Dyslipidemia is the main factor in the initiation and progression of atherosclerosis. The search for probable factors aff ecting lipid metabolism is relevant. The aim of the study was to evaluate the parameters of lipid metabolism in the blood serum of men exposed to elevated noise levels. Material and methods. 293 men with no confi rmed atherosclerotic cardiovascular diseases were examined. Among the surveyed, 2 groups were identifi ed: 203 men who work under the infl uence of noise, and 90 men who do not come into contact with harmful production factors. Total cholesterol, triglycerides, low- and high-density lipoproteins, and the level of oxidized low-density lipoproteins were determined. Remnant cholesterol, atherogenic index and atherogenic plasma index were calculated. Results. Among persons under 55 years of age working in noise, an increase in total cholesterol (p = 0.02) and remnant cholesterol (p = 0.0006), a decrease in high-density lipoproteins (p = 0.03) and a tendency to increase the atherogenic index (p = 0.05) and the atherogenic plasma index (p = 0.07) were revealed. The prevalence of hypercholesterolemia was comparable in the main and control groups and amounted to 56.7 and 47.4%, respectively (p = 0.17). The median level of oxidized low-density lipoproteins in people working with noise did not exceed the upper limit of the norm. Conclusions. In men younger than 55 years old, working under conditions of exposure to increased noise levels, some features of the blood lipid spectrum are observed. The revealed changes may indicate an increase in the atherogenic potential of the blood serum