Features of Protein-Protein with Protein-RNA Interactions in Bacteria and Fungi

Abstract

Various protein-protein and protein-RNA interactions are extant which are fundamental for the regulation of biosynthetic pathways, metabolic and cellular processes in bacteria, fungi and other microorganisms, but their role and significance must be clearly elucidated. To effectively and efficiently compete in their natural habitat or niche, bacteria, fungi, and other microorganisms utilize regulatory mechanisms in metabolic production and other cellular processes; thus controlling overproduction and excretion of the secondary metabolites of excess concentrations into the environment. The knowledge and information regarding fungal natural product biosynthesis have been retarded in comparison to the corresponding extant bacterial biosynthetic pathways due to salient externalities, constraints and challenges.