Abstract
The objective: to set influence of organ-preserving operations on the organs of small pelvis on the state of ovarian reserve. Materials and methods. An inspection is conducted 100 patients of reproductive age, interested in the fertility preservation, after organ-preserving operative interferences on the organs of small pelvis. The age of the patients varied from 22 to 44 years, making, on the average, 33,1±0,8 years. Conducted the general clinical-and-echographic inspection of patients with the study of heredity, carried somatic and gynaecological diseases, features of menstrual and reproductive function, and also estimation of hormonal status. For determination of autoantibodies to the antigens of ovary used the method of indirect immunoenzyme analysis (ELISA).Results. For the women of reproductive age, which carried organ-preserving, surgical interferences on the organs of small pelvis concerning the of high quality diseases of ovaries, uterus and isolated pipe peritoneal factor of infertility during 6 months after an operation there is violation of functional activity of ovaries exhaustion of ovarian reserve. The most expressed changes are observed at initial pathology of ovaries.During 6 months after organ-preserving operative interferences on the organs of small pelvis for the patients of reproductive age, regardless of nosology, hypergonadotropic hypogonadism is formed from hypoestrogenism and hypoandrogenism, and also decline of ovarian reserve (in 4 times), not conditioned by autoimmune aggression. The found out the changes of parameters of hormonal status answer the clinical picture of premature exhaustion of function of ovaries. For the maintaining of the functional state of ovaries and ovarian reserve of the use of laparotomy as operative access more spares, that it follows to take into account at operative interferences on the organs of small pelvis for the women of reproductive age, interested in realization of reproductive function. At the choice of laparoscopy as access at organ-preserving operations on the organs of small pelvis of the use of monoarctic electrosurgery more spares from positions of maintaining of ovarian reserve, that it follows to take into account for the women of reproductive age interested in realization of reproductive function.Conclusions. The got results it follows to draw on at development of algorithm of diagnostic, treatment-and-prophylactic and recovery measures.Keywords: ovarian reserve, ovarian surgery.
Published Version
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