FEATURES OF OBTAINING GELS BASED ON AGAR-AGAR FOR COSMETOLOGY AND MEDICINE WITH ANTIBACTERIAL PROPERTIES

Abstract

In the modern world, special attention is paid to materials with controlled characteristics. In this aspect, polymers and materials based on them have a number of specific properties for effective use in medicine and cosmetology. Humic substances satisfy most of these features, so their use is very important. The study of the features of the processes of gelation in polymer systems such as agar-agar, which has rather universal properties, makes it possible to use it as a basis for gels and polymer carriers, as well as in the processes of obtaining medical and cosmetic materials with different properties, which can be important in solving a number of topical issues. In particular, these are lightweight and cheap to manufacture antiseptic gels, dressings on wounds with absorption and protective properties, all kinds of cosmetics. In the article, a study was carried out to study the processes of gelation and the features of the rheological properties of hydrogels based on agar-agar in order to obtain modern hydrogels with an antibacterial effect. It was found that the introduction of humic acids into the composition of polymer hydrogels slows down the processes of structure formation, which leads to a decrease in the viscosity of all the studied compositions. Also, a decrease in the melting temperature of hydrogel jellies with an increase in the content of humic acids in them indicates a reduced level of gelation, which also leads to an increase in the time of loss of stickiness of polymer hydrogels. It has been shown that humic acids in polymer hydrogels have high antibacterial activity and almost completely stop the processes of mold formation in them. It was found that the most effective from the point of view of obtaining hydrogels with an antibacterial effect are agar-agar compositions with a humic acid content of 15 %. Thus, cosmetic polymer hydrogels with an antibacterial effect have been developed, which can be used in the treatment of hands, face and other areas of the skin that are open and contact for humans to combat coronavirus bacteria.