Features of changes in the heart, blood vessels and internal organs in men with hypertension, depending on the value of the body mass index

Abstract

Objective: study of the features of changes in the heart, blood vessels and internal organs (liver and kidneys) in men with hypertension, depending on the BMI value. Materials and methods: 194 men aged 25 to 63 with hypertension were examined. All the examined patients were divided into 3 groups depending on the BMI value. All patients included in the study were determined by serum creatinine (calculated by GFR), glucose, aspartate aminotransferase, alanine aminotransferase, lipid spectrum, uric acid. In addition, echocardiography, ultrasound of the kidneys with measurement of arterial and venous blood flow through the main vessels of the kidneys, ultrasound of the liver were performed. In the future, the groups were compared with each other according to the studied laboratory and instrumental data. Results: as the BMI values increased, the indicators of alanylaminotransferase, IFDS, RWT LV, MMLV, IMLV, the size of the right lobe of the liver, the incidence of hepatosteatosis significantly increased. Adherence to antihypertensive therapy in the selected groups ranged from 18,9 to 20,5%. Bilateral disorders of outflow through the renal veins were 1,8 times more common among people with normal BMI compared with obesity (p<0.05). Conclusion: among the examined young men with hypertension, there are features of an unfavorable "cardiological" profile and low adherence to antihypertensive therapy, which, as the age and length of the disease increases, is associated with a high risk of developing associated clinical conditions in the future. In male patients with hypertension and obesity, the incidence of hepatosteatosis is 100%, having an additional adverse effect on cardiovascular risk. The revealed features of renal venous blood flow among patients with hypertension deserve further investigation.