Abstract

Feasibility study of an electro-optical absorption based method for the measurement of endogenous chemicals in living and ex-vivo tissues

Highlights

  • In vivo analysis of neurotransmitter activities are based upon electro-chemical methods that require Invasive implantation of electrodes or probes within the animal’s brain

  • The principle of this technique is the detection of the optical absorption, by the tissue under test, of radiation at given wavelengths

  • Illumination of the tissue and detection of diffused radiation can occur by means of an optical fiber or, to reduce invasiveness, across the skin or possibly a thin bone layer

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Summary

Introduction

In vivo analysis of neurotransmitter activities are based upon electro-chemical methods that require Invasive implantation of electrodes or probes within the animal’s brain. The principle of this technique is the detection of the optical absorption, by the tissue under test, of radiation at given wavelengths. Illumination of the tissue and detection of diffused radiation can occur by means of an optical fiber or, to reduce invasiveness, across the skin or possibly a thin bone layer.

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