Abstract
323 Background: Overlap volume histogrmas (OVHs) allow for new plans to be generated based upon prior similar treatment plans. The purpose of this project was to clinically deploy a generic and user-friendly interface for using a database populated with OVHs for planning SBRT pancreas patients. An interface for evaluating adherence to protocol tolerances is also developed to aid in the planning process. Methods: A database of previously treated SBRT pancreas patients is used to query the organ at risk (OAR) dose from patients with similar or harder to plan OVHs. For each OAR in a new plan, the database is queried to find the lowest achievable structure dose from all previous patients with a greater than or equal overlap between the selected structure and the target structure. Queried values are then automatically loaded into the inverse planning optimizer objectives and used to generate an optimized plan. Plans are then evaluated using a protocol interface which queries relevant protocol values and displays the values in a color-coded interface. Upon plan completion the system submits the new patient data to the OVH database and stores relevant DVH metrics in the MOSAIQ database for tracking. Results: The interface has been used to successfully plan 5 SBRT patients. All planned patients met protocol requirements. Automatic plans required fewer iterations to produce an acceptable plan. The physician indicated preference to the automatically generated plans due to better adherence to protocol requirements and lower critical structure doses. Conclusions: Automatic planning can be used to generate clinical plans which reduce dose to normal tissues while achieving the dose distribution required by clinical protocols. The protocol interface allows for more rapid evaluation of plan acceptability during planning and for physician review. The system can be deployed clinically, but requires adherence by all participants to standard naming conventions for targets and OARs.
Published Version
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