Fe-doped WO3-Modified sensor for the improved electrochemical detection of curcumin

Abstract

In this study, an iron-doped tungsten oxide (Fe-WO3) nanomaterialwas synthesizedand utilized to modify carbon paste electrodes for the identification of the bioactive ingredient curcumin (CUM). Turmeric contains a bioactive compound called curcumin, which is yellow and has various potential biological applications, such as being an anti-carcinogenic, anti-inflammatory, and antioxidant agent. The Fe-WO3 nanomaterial underwent characterization through SEM, XRD, and EDS techniques. The electrochemical performance of CUM was inquired using square wave and cyclic voltammetry methods. During catalytic oxidation, the Fe-WO3 working electrode assembly showed faster electron transport than the bare CPE. Investigations havebeen conductedinto the kinetics of oxidation, and the developed sensor demonstrated an excellent linear detection range (5 μM to 60 μM), a decreased limit of detection (6.2 × 10−8 M), and a limit of quantification under optimal conditions (20.7 × 10−8 M).The numbers of electrons transmitted, the heterogeneous rate constant, the electron transfer coefficient, and the electrochemical oxidation were all measured. The results from the examination of CUM in actual samples using the devised Fe-doped WO3 modified electrode were good. Additionally, it showed a considerable increase in the curcumin peak current concerning responsively, specificity, and reliability for curcumin analysis.