Fe doped MoS2/polypyrrole microtubes towards efficient peroxidase mimicking and colorimetric sensing application.

Abstract

Molybdenum disulfide (MoS2) nanosheets have been found to exhibit intrinsic peroxidase-like activity that could be applied in colorimetric sensing platforms. However, their poor conductivity and few exposed edge sites often lead to poor catalytic activity, impeding the application of MoS2 nanosheets in enzyme-like catalysis. Here, a novel strategy was developed to selectively deposit Fe-doped MoS2 nanosheets on polypyrrole microtubes to obtain Fe-MoS2@PPy microtubes to address these issues. In the synthesized Fe-MoS2@PPy microtubes, PPy microtubes can not only be used as a conductive support to promote the electron transfer, but also greatly alleviate the aggregations of MoS2 nanosheets, and thus improve the enzyme-like activity. Meanwhile, additional active sites, formed by Fe doping, also endow the catalyst with excellent activity in enzyme-like catalysis. Notably, in the process of sulfidation, the dissolution, redistribution and diffusion result in the disappearance of MoO3@FeOOH cores and the formation of Fe doped MoS2 nanosheets, which significantly facilitate the deposition of Fe-doped MoS2 nanosheets on PPy microtubes. On the basis of the high peroxidase-like catalytic efficiency of the Fe-MoS2@PPy microtubes, a simple and convenient colorimetric strategy for the rapid and sensitive detection of L-cysteine has been developed. This strategy introduces both the PPy layer and Fe doping to increase the conductivity and the density of active sites of MoS2 nanosheets, thus enhancing the catalytic activity and stability. More importantly, Fe-MoS2@PPy microtubes could be used as a good support for loading other materials such as Au and Ag nanoparticles (NPs), forming ternary Fe-MoS2/Ag, Au@PPy nanotubes. This work offers an opportunity to develop low-cost and highly active MoS2-based nanocomposites for promising potential applications in electrochemical energy conversion and medical diagnostics.