Abstract
The effects of cold acclimation and repetitive intermittent immobilization were examined on fatty acid (FA) compositions in phospholipids of rat interscapular brown adipose tissue (BAT) and plasma. As previously reported, cold acclimation and intermittent immobilization increased the degree of unsaturation as a whole in FAs of BAT but not in plasma. N-3 polyunsaturated docosahexaenoic acid (22-6; DHA) decreased in cold acclimation but increased in intermittent immobilization in phospholipids of BAT. DHA was decreased in phospholipids of plasma in both groups. Considering our previous findings that the in vitro thermogenic response of BAT was suppressed in cold acclimation and enhanced in intermittent immobilization, it was inferred that DHA in BAT is involved in the regulation of thermogenic function of this tissue.
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