Abstract

THE BILL & MELINDA Gates Foundation is committing $100 million over five years to add a fast-track grant arm to its global health philanthropy efforts. Called Grand Challenges Explorations, the initiative is intended to encourage scientists to pursue unorthodox ideas that could lead to new vaccines, diagnostics, and drugs for people in poor countries. The program expands the foundation’s Grand Challenges in Global Health initiative, which was launched in 2003 to take on 14 specific global health problems, including improving the delivery and stability of vaccines and stopping insects that transmit diseases. But the new initiative will differ from the larger program by offering scientists small sums of cash—awards will be up to $100,000—to validate what the foundation calls “creative, unorthodox” ideas. Funding proposal applications will be short and, once submitted, on a fast-track for review. The initiative ties into a trend among nonprofits of finding creative ways to finance cutting-edge research in di...

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