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Abstract
The probing technique for the specific binding of proteins and antibodies plays a crucial role in the domains of biotechnology, medicine, and pharmacology. The development of rapid and highly sensitive probing technique for specific interactions remains an enduring focus. This paper presents a quantum weak measurement technique for rapid and highly sensitive detection of protein-antibody specific binding, effectively reducing noise and achieving measurement accuracy approaching the standard quantum limit. The speed of our detection technology is determined by the response time of the dual-channel detection, which can reach nanoseconds. The results show that the detection limit can reach 26 ng/ml, and the detection range is 0∼3.44μg/ml. The quantum weak measurement technique developed in this study offers a heuristic approach for protein-antibody interaction detection with broad application prospects.
Published Version
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