False alarms during recognition of famous people from faces and voices in patients with unilateral temporal lobe resection and normal participants tested after anodal tDCS over the left or right ATL

Abstract

Data gathered in the field of the experimental social psychology have shown that it is more difficult to recognize a person through his/her voice than through his/her face and that false alarms (FA) are produced more in voice than in face recognition. Furthermore, some neuropsychological investigations have suggested that in patients with damage to the right anterior temporal lobe (ATL) the number of FA could be higher for voice than for face recognition.In the present study we assessed FA during recognition of famous people from faces and voices in patients with unilateral ATL tumours and in normal participants tested after anodal transcranial direct current stimulation (tCDS), over the left or right ATL. The number of FA was significantly higher in patients with right than in those with left temporal tumours on both face and voice familiarity. Furthermore, lesion side did not differentially affect patient's sensitivity or response criterion when recognizing famous faces, but influenced both these measures on a voice recognition task. In fact, in this condition patients with right temporal tumours showed a lower sensitivity index and a lower response criterion than those with left-sided lesions. In normal subjects, the greater right sided involvement in voice than in face processing was confirmed by the observation that right ATL anodal stimulation significantly increased voice but only marginally influenced face sensitivity. This asymmetry between face and voice processing in the right hemisphere could be due to the greater complexity of voice processing and to the difficulty of forming stable and well-structured representations, allowing to evaluate if a presented voice matches or not with an already known voice.