Abstract
<p><strong><em>Background</em></strong><em>: Parkinson's disease (PD) is a chronic neurodegenerative disease that manifests as movement disorders. Based on motor symptoms, PD is classified into subtypes of tremor and postural instability gait disorders (PIGD). The motor symptoms subtype is a predictor of disease progression, therapeutic response, and quality of life for Parkinson's patients. The purpose of this study is to identify some factors that influence motor symptoms in Parkinson's disease.</em><strong><em>Methods:</em></strong><em> This research use cross sectional design. Samples were selected by consecutive sampling method that met the inclusion and exclusion criteria. Research subjects were 58 people. Statistical analysis using SPSS. p values &lt;0.05 were considered statistically significant.</em><strong><em>Results:</em></strong><em> This research include 58 patients, 55.2% were men with range of age 63.5 ± 8.5 years old. The mean age at onset was 57.9 ± 9.5 years and duration of disease 6.1 ± 4.6 years. Motor symptoms 53.4% dominant tremor. There was a significant relationship between disease stage and motor symptom subtypes (p &lt;0.001). There is no relationship between the patient's age, age at onset and duration of the disease with motor symptom subtypes.</em><strong><em>Conclusions:</em></strong><em> There is a relationship between disease stage and motor symptom. The patient's age, age at onset and duration of the disease are not related to the motor symptoms of Parkinson's patients.</em></p>
Highlights
Background: Parkinson's disease (PD) is a chronic neurodegenerative disease that manifests as movement disorders
PD is classified into subtypes of tremor and postural instability gait disorders (PIGD)
The motor symptoms subtype is a predictor of disease progression, therapeutic response, and quality of life for Parkinson's patients
Summary
Subtipe gejala motorik merupakan prediktor progresivitas penyakit, respon terapi, dan kualitas hidup pasien Parkinson. Tujuan penelitian ini mencari faktor- faktor yang mempengaruhi subtipe gejala motorik penyakit Parkinson. Metode: Penelitian ini menggunakan desain cross sectional. Sampel dipilih dengan metode consecutive sampling yang memenuhi kriteria inklusi dan ekslusi. Hasil: Dari 58 pasien, 55.2% laki-laki dengan rerata usia 63.5 ± 8.5 tahun. 9 ± 9.5 tahun dan durasi penyakit 6.1 ± 4.6 tahun. Terdapat hubungan yang bermakna stadium penyakit dengan subtipe gejala motorik (p < 0.001). Tidak terdapat hubungan usia pasien, usia saat onset dan durasi penyakit dengan subtipe gejala motorik. Kesimpulan: Terdapat hubungan stadium penyakit dengan subtipe gejala motorik. Usia saat onset dan durasi penyakit tidak berpengaruh pada gejala motorik pasien Parkinson
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