Abstract
Summary o 1. A canine irreversible hemorrhagic shock preparation is described. It is produced by lowering the blood pressure to 20 mm. Hg for 40 minutes in the anesthetized, ventilated animal, followed by retransfusion of the shed blood in 15 minutes. 2. Arterio-arterial counterpulsation in animals subjected to hemorrhagic shock caused increased diastolic and decreased systolic pressures. This is known to increase coronary perfusion and decrease the pressure work of the heart. Measurements of flow and cardiac function studied showed no significant differences in the control and counterpulsated groups. 3. It would seem that improvement in coronary perfusion and decreased pressure work of the heart failed to alter the course of the experimental animal with hemorrhagic shock.
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