Abstract

Backgroun: Intrauterine fetal death (IUFD) is a contributor of perinatal outcome and is an important indicator of the quality of antenatal care. Despite efforts, risk factors cannot be identified in cases of intrauterine fetal deaths. This study aims to identify the maternal, fetal, placental and cord related factors related to it. 
 Methods: It is a retrospective cross-sectional study conducted analyzing patients admitted with IUFDs after 28 weeks of pregnancy at Tribhuwan University Teaching Hospital from April 2019 to March 2020. It was conducted after taking ethical approval from Institutional Review Committee (IRC) of Institute of Medicine. Data were collected from review of charts of individual patients in MS Excel and was analyzed using SPSS.
 Results: There were 5496 births and 46 intrauterine fetal deaths during the study period giving stillbirth rate of 8 per 1000 births. It was common in the age group of 26-30 years (34.8%), 62.2% were from inside Kathmandu valley,43.5% were just literate, 13% were illiterate, 84.8% were housewives, 56.5% were primigravida and 69.57% of the babies were preterm. Only four percent had previous history of intra uterine fetal deaths. Hypertensive disorders complicating pregnancy were found in 30.5% followed by heart disease in 10.9% of the mothers. There were no known co-morbidities in 26.1% of the patients. Out of total 46 cases, 62% were female. Two had Rh isoimmunization and four had congenital malformations. Placenta previa was seen in four percent and abruptio placenta in two percent. Twin pregnancy with diamniotic dichorionic placenta was present in four percent. Seventeen percent of the babies had cord around the neck and two percent had thrombosis of the umbilical cord. 
 Conclusion: Low level of maternal education and maternal comorbidities like hypertensive disorders complicating pregnancy were found to be most common factors seen in cases of intrauterine fetal deaths.

Highlights

  • Fetal death is defined as death prior to complete expulsion or extraction of fetus irrespective of gestational age and is not induced termination of pregnancy.[1]

  • Factors related to late intrauterine fetal death in a tertiary referral center: A Retrospective Study

  • This study aims to find out the prevalence, and identify and quantify the maternal, fetal, placental, and cord related factors in cases of Intra Uterine Fetal Death (IUFD) admitted in Tribhuvan University Teaching Hospital (TUTH)

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Summary

Introduction

Fetal death is defined as death prior to complete expulsion or extraction of fetus irrespective of gestational age and is not induced termination of pregnancy.[1]. It is suggested to report fetal deaths at 20 or more weeks or weight greater than or equal to 350 grams if the gestational age is not known.[3] In a developing country like Nepal, the period of viability for a fetus is later than that in a developed country and IUFD can be defined as fetal death occurring after 28 weeks period of gestation.[4] Stillbirth is a significant contributor of perinatal mortality and is defined by WHO as the number of stillbirth and deaths in the first week of life per 1000 live births. Risk factors cannot be identified in cases of intrauterine fetal deaths. This study aims to identify the maternal, fetal, placental and cord related factors related to it

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