Factors predicting clinical outcome during hospitalization after pericardiocentesis in Sanglah General Hospital, Bali, Indonesia

Abstract

Background: Even though pericardiocentesis is a routine life-saving procedure for massive pericardial effusion, there is scarce data regarding risk factors predicting the outcome in patients undergoing pericardiocentesis. This study aimed to investigate the role of various clinical, demographic, and laboratory risk factors as a predictor of in-hospital mortality and Major Adverse Cardiac Events (MACE) in patients undergoing pericardiocentesis at Sanglah General Hospital, Bali, Indonesia. Methods: Prospective cohort study with consecutive sampling was conducted in patients undergoing pericardiocentesis in Sanglah General Hospital, Bali, Indonesia, from May 2017 until September 2021. Risk factors and blood samples were observed and measured at the first admission. MACE and in-hospital mortality were observed during hospitalization. Data were analyzed using SPSS version 23 for Windows. Results: Twenty-seven patients were involved in this study. Malignant etiology was associated with increased risk of in-hospital mortality with HR 13.459 (95%CI: 1.378-131.49). Respiratory Failure during admission was associated with increased risk of mortality with HR 5.99 (95% CI: 1.355-26.55) and increased risk of persistent pericardial effusion HR 5.72 (95% CI: 1.570-20.800). Conclusion: Malignant etiology and respiratory Failure are independent predictors of in-hospital mortality in patients undergoing pericardiocentesis in Sanglah General Hospital. Respiratory Failure was associated with an increased risk of persistent pericardial effusion.