Abstract
The stimulation of the D-(1-14C)glucose and D-(6-14C)glucose metabolism in pig leucocytes during the phagocytosis of bacteria and inert particles was studied. The following results were obtained: 1. The magnitude of phagocytosis-stimulated glucose oxidation is directly related to the nature and number of particles added. 2. Live bacteria stimulate the glucose metabolism to a greater extent than do a similar number of heat-killed organisms. As to the extent of the stimulation the species of bacteria offered for phagocytosis is crucial. 3. After in vitro addition of a lipopolysaccharide a stimulating effect is observed, a depression has been shown after the addition of hydrocortisone.
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