Abstract
Artificially induced sensitivity to Ascaris lumbricoides antigen was found to have disappeared in 79 per cent of 33 subjects tested two years after sensitization. Among 25 of these negative reactors who were subjected to a second series of sensitizing injections, the average time for the reappearance of immediate positive skin reactions was 2.8 weeks as compared to 5.9 weeks in their former sensitization. This more rapid response is interpreted as an anamnestic response involving the skin-sensitizing antibody. The possible significance of these findings in interpreting the results of previous studies dealing with race and sex factors in sensitization to Ascaris antigen is discussed.
Published Version
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