Factors influencing prognosis of cerebral venous thrombosis patients with intracranial hematoma

Abstract

Objective To explore the factors that may influence the prognosis of patients with cerebral venous thrombosis (CVST) combined with intracranial hematoma (ICH). Methods Twenty-eight consecutive patients with CVST combined with ICH, admitted to our hospital from April 2007 to April 2017, were chosen in our study; 17 accepted combined treatment (endovascular treatment combined with anticoagulation therapy or endovascular treatment combined with surgery) and 11 of them accepted single therapy (anticoagulation therapy or surgery). Their clinical data were retrospectively reviewed. Follow-up outcomes were evaluated using modified Rankin Scale (mRs) and risk factors of recurrence were analyzed. Results Fifteen patients had good outcomes and 13 had poor outcomes. As compared with patients with good outcomes, patients with poor outcomes had significantly higher incidence rate of disturbance of consciousness, statistically higher percentages of hematoma volume >30 mL and midline shift>10 mm and ratio of single treatment (P<0.05). Conclusions The prognoses of CVST patients with ICH may be influenced by disturbance of consciousness, hematoma volume>30 mL, midline shift>10 mm and treatment protocol. Key words: Cerebral venous sinus thrombosis; Endovascular treatment; Anticoagulation