Abstract
Objectives: Minimal stimulation is a protocol first described for non-ART infertility treatment in 1996 (Fertil Steril, 1996;65:583–587), consisting of 5 days of clomiphene citrate (100 mg/day) followed by a single dose of gonadotropin (150 U) on cycle day 9. In our clinic, this protocol has been used in combination with intrauterine insemination (IUI). The published description of this protocol (61 women, 106 cycles) showed a favorable pregnancy rate (20.8%) in a young population (mean age = 31.9) with a high rate of ovulatory dysfunction (40%). The objectives of the current study were: (1) to determine the effectiveness of this protocol in the general infertility population cared for in a university-based infertility practice and (2) to evaluate factors influencing pregnancy rates obtained with this MS protocol.
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