Factors Influencing Higher-order Aberrations in Young Myopes

Abstract

Purpose : To investigate the effects of age, refractive errors, corneal refractive power, pupil diameter, and pupil center shift on high-order aberrations (HOAs) in young myopic eyes. Methods : The myopic eyes of aged 20 to 39 years who had no ophthalmologic diseases and refractive surgery were recruited. I-Profilerplus (Zeiss, Berlin, Germany) was used to measure HOAs and refractive errors, corneal refractive power, pupil diameter, and pupil shift, and factors affecting HOA were analyzed. Results : In young myopes, as the age increased, the total HOA was increased in the positive (+) direction (p<0.001), and the horizontal coma, vertical coma, and spherical aberration (SA) were increased in the negative (-) direction (all, p<0.001). As the equivalent spherical refractive errors increased in the negative (-) direction, the total HOA was increased in the negative (-) direction (p<0.001), and the SA was increased in the positive (+) direction (p=0.004). As the mean corneal refractive power increased, the total HOA and SA were increased in the negative (-) direction (p<0.001, p=0.025), and the horizontal coma and vertical coma aberration were increased in the positive (+) direction (p=0.001, p<0.001). As the pupil diameter increased, vertical trefoil and SA were increased in the positive (+) direction (all, p<0.001). As the pupil center shift increased toward the lateral, the horizontal coma aberration increased in the positive (+) direction (p=0.003), and as the pupil center shift increased toward the superior, the vertical coma aberration increased positive (+) direction (p<0.001). Conclusion : The ocular HOAs of the young myopes changes according to age, refractive error, corneal refractive power, pupil size, and pupil center shift and the results in this study would be cornerstones in designing lenses for spectacle and contact lens.